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Article

High expression of ETS2 predicts poor prognosis in acute myeloid leukemia and may guide treatment decisions

19 Jul 2017

Abstract excerpt

ETS2 is a downstream effector of the RAS/RAF/ERK pathway, which plays a critical role in the development of malignant tumor. However, the clinical impact of ETS2 expression in AML remains unknown. In this study, we evaluated the prognostic significance of ETS2 expression using two relatively large cohorts of AML patients. In the first cohort, compared to low expression of ETS2 (ETS2 low), high expression of ETS2...

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PMID: 28724426
DOI: 10.1186/s12967-017-1260-2

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