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Article

TET2 expression is a potential prognostic and predictive biomarker in cytogenetically normal acute myeloid leukemia

8 Dec 2017

Abstract excerpt

TET2 (Ten-Eleven Translocation 2) gene is a member of TET family that can modify DNA through catalyzing the conversion of 5-methylcytosine (5-mC) into 5-hydroxymethylcytosine (5-hmC). Although TET2 mutation has been disclosed in a variety of hematopoietic malignancies, the prognostic implication of TET2 expression in acute myeloid leukemia (AML) remains largely elusive. In this study, real-time quantitative PCR...

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Identifiers

PMID: 29219176
DOI: 10.1002/jcp.26373

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