Article
Identification of G2607A mutation in EGFR gene with a significative rate in Moroccan patients with Bladder Cancer.
Cellular and molecular biology (Noisy-le-Grand, France) - 20 May 2017
El Hamdani W, Hadami K, Bensaid M, El Ahanidi H, Ameur A, Filali Maltouf A, Abbar M, Attaleb M, Albouzidi A, El Mzibri M
Abstract excerpt
The epidermal growth factor receptor (EGFR) is involved in the regulation of several cellular processes and in the development of many human cancers. Somatic mutations of EGFR at tyrosine kinase domain have been associated with clinical response to tyrosine kinase inhibitors (TKIs) in lung cancer patients. In this study, we evaluated the frequency of point mutations in EGFR for future use of TKI in clinical...
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