Article
Identification of G2607A mutation in EGFR gene with a significative rate in Moroccan patients with nasopharyngeal carcinoma.
Cellular and molecular biology (Noisy-le-Grand, France) - 15 Dec 2010
Naji F, Attaleb M, Laantri N, Benchakroun N, El Gueddari B, Benider A, Azeddoug H, Ennaji M M, El Mzibri M, Khyatti M
Abstract excerpt
The epidermal growth factor receptor (EGFR) is involved in the regulation of several cellular processes and in the development of many human cancers. Somatic mutations of EGFR at tyrosine kinase domain have been associated with clinical response to tyrosine kinase inhibitors (TKIs) in lung cancer...
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