Article
EGFR 3'UTR 774T>C polymorphism contributes to bladder cancer risk.
Mutagenesis - 1 Jan 2013
Chu Haiyan, Wang Meilin, Jin Hua, Lv Qiang, Wu Dongmei, Tong Na, Ma Lan, Shi Danni, Zhong Dongyan, Fu Guangbo, Yuan Lin, Qin Chao, Yin Changjun, Zhang Zhengdong
Abstract excerpt
Much evidence show that over-expression of epidermal growth factor receptor (EGFR) plays an important role in regulating carcinogenesis. Genetic variations in 3' untranslated region (3'UTR) of gene have been reported to affect gene expression by interfering with microRNAs (miRNAs), which are thought to function as either tumour suppressors or oncogenes by binding to their target mRNA. In this study, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
