Article
Haplotype-based association of Vascular Endothelial Growth Factor gene polymorphisms with urothelial bladder cancer risk in Tunisian population.
Journal of clinical laboratory analysis - 1 Nov 2018
Ben Wafi Safa, Kallel Amani, Ben Fradj Mohamed Kacem, Sallemi Ahmed, Ben Rhouma Sami, Ben Halima Meriam, Sanhaji Haifa, Nouira Yassine, Jemaa Riadh, Feki Moncef
Abstract excerpt
BACKGROUND/AIM: Accumulated data suggested that Vascular Endothelial Growth Factor is a major mediator in vasculogenesis, angiogenesis and recently in tumorigenesis. Therefore, we aimed to investigate for the first time the association between VEGF gene variants (-2549I/D (rs35569394), -2578C/A (rs699947), and +936C/T (rs3025039)) with urothelial bladder cancer (UBC) in Tunisian population. METHODS: A total of...
Read the complete abstract on PubMed