Article
Re-evaluating the FGFR4 (G388R) germline mutation in different cancers in Pakistani population.
Journal of experimental therapeutics & oncology - 1 Jan 2013
Mansoor Qaisar, Fayyaz Sundas, Farooqi Ammad Ahmad, Bhatti Shahzad, Ismail Muhammad
Abstract excerpt
BACKGROUND: Cancer is a life threatening complicated diseasethatarises because of wide-ranging environmental and cellular factors. These external and internal stresses disrupt the spatio-temporally controlled mechanisms of the cellular signalings. Accumulating evidence suggests that signal transductions are misrepresented in carcinogenesis and FGFR4 is reported to be involved in carcinogenesis. Although there is...
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