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Article

Microevolution of the major common Pseudomonas aeruginosa clones C and PA14 in cystic fibrosis lungs.

Environmental microbiology - 1 Jul 2011

Cramer Nina, Klockgether Jens, Wrasman Kristie, Schmidt Mario, Davenport Colin F, Tümmler Burkhard

Abstract excerpt

Clones C and PA14 are the worldwide most abundant clonal complexes in the Pseudomonas aeruginosa population. The microevolution of clones C and PA14 was investigated in serial cystic fibrosis (CF) airway isolates collected over 20 years since the onset of colonization. Intraclonal evolution in CF lungs was resolved by genome sequencing of first, intermediate and late isolates and subsequent multimarker SNP...

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PMID: 21492363
DOI: 10.1111/j.1462-2920.2011.02483.x

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