Article
Molecular Epidemiology of Mutations in Antimicrobial Resistance Loci of Pseudomonas aeruginosa Isolates from Airways of Cystic Fibrosis Patients.
Antimicrobial agents and chemotherapy - 1 Nov 2016
Greipel Leonie, Fischer Sebastian, Klockgether Jens, Dorda Marie, Mielke Samira, Wiehlmann Lutz, Cramer Nina, Tümmler Burkhard
Abstract excerpt
The chronic airway infections with Pseudomonas aeruginosa in people with cystic fibrosis (CF) are treated with aerosolized antibiotics, oral fluoroquinolones, and/or intravenous combination therapy with aminoglycosides and β-lactam antibiotics. An international strain collection of 361 P. aeruginosa isolates from 258 CF patients seen at 30 CF clinics was examined for mutations in 17 antimicrobial susceptibility...
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