Article
Interleukin-8 and CXCR1 receptor functional polymorphisms and susceptibility to acute pyelonephritis.
The Journal of urology - 1 Mar 2007
Artifoni Lina, Negrisolo Susanna, Montini Giovanni, Zucchetta Pietro, Molinari Pier Paolo, Cassar Walburga, Destro Roberta, Anglani Franca, Rigamonti Waifro, Zacchello Graziella, Murer Luisa
Abstract excerpt
PURPOSE: We performed a case-control study in children diagnosed by the first episode of upper urinary tract infection with or without vesicoureteral reflux to evaluate the association of functional polymorphism of interleukin-8 (-251A>T and +2767A>G), and its receptor CXCR1 (+2607G>C). MATERIALS AND METHODS: Genomic DNA was obtained from 265 children with a clinical and laboratory diagnosis of urinary tract...
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