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Article

An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida.

Neuromolecular medicine - 1 Sept 2017

Zhang Jun, Dai Xiao-Lu, Liu Gui-Cen, Wang Juan, Ren Xue-Yi, Jin Mu-Hua, Mi Nan-Nan, Wang Shu-Qin

Abstract excerpt

Maternal genetic variants of enzymes in folate-homocysteine metabolic network are significantly correlative with the risk of spina bifida. To survey the genetic causality, the genotypes of three women having spina bifida fetuses from two unrelated Chinese families were screened in candidate alleles. Polymerase chain reaction, capillary electrophoresis and Sanger sequencing were employed to recognize the allelic...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Ferredoxin-NADP Reductase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folic Acid

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Source

Identifiers

PMID: 28712006
DOI: 10.1007/s12017-017-8452-z

Genes

MTRR
MTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida.PMID 28712006Read ↗

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