Article
Listeria monocytogenes PdeE, a phosphodiesterase that contributes to virulence and has hydrolytic activity against cyclic mononucleotides and cyclic dinucleotides.
Microbial pathogenesis - 1 Sept 2017
Reddy Swetha, Turaga Gokul, Abdelhamed Hossam, Banes Michelle M, Wills Robert W, Lawrence Mark L
Abstract excerpt
We have identified and partially characterized a putative HD domain hydrolase, LMOf2365_2464, which is highly expressed during listerial intracellular replication. LMOf2365_2464 is annotated as a putative HD domain-containing hydrolase. The ability of an isogenic mutant strain, F2365Δ2464, to adhere, invade and replicate in intestinal epithelial cells (Caco-2) was significantly lower than parent strain F2365....
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