Article
Deciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling.
BMC genomics - 18 Oct 2010
Schauer Kristina, Geginat Gernot, Liang Chunguang, Goebel Werner, Dandekar Thomas, Fuchs Thilo M
Abstract excerpt
BACKGROUND: The human pathogen Listeria monocytogenes resides and proliferates within the cytoplasm of epithelial cells. While the virulence factors essentially contributing to this step of the infection cycle are well characterized, the set of listerial genes contributing to intracellular replication remains to be defined on a genome-wide level. RESULTS: A comprehensive library of L. monocytogenes strain EGD...
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