Differential TBXA2 receptor transcript stability is dependent on the C924T polymorphism.

doi:10.1016/j.prostaglandins.2017.07.001

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Article

Differential TBXA2 receptor transcript stability is dependent on the C924T polymorphism.

Prostaglandins & other lipid mediators - 1 Jan 2018

De Iuliis Vincenzo, Ursi Sebastiano, Pennelli Alfonso, Caruso Marika, Nunziata Angela, Marino Antonio, Flati Vincenzo, Cipollone Francesco, Giamberardino Maria Adele, Vitullo Gianfranco, Toniato Elena, Conti Pio, Martinotti Stefano

Abstract excerpt

BACKGROUND: In order to better characterize the molecular mechanisms involved in processing mutated transcripts, we investigated the post-transcriptional role of the C924T polymorphism (rs4523) located in the 3' region of the TBXA2R gene. METHODS AND RESULTS: Experiments of dose response with Actinomycin D on MEG-01 human cell line showed a significant decrease on cell viability that was more evident on cells...

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PMID: 28709878
DOI: 10.1016/j.prostaglandins.2017.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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