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Article

Characterization of susceptibility variants of poliovirus grown in the presence of favipiravir.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Oct 2018

Daikoku Tohru, Mizuguchi Mineyuki, Obita Takayuki, Yokoyama Takeshi, Yoshida Yoshihiro, Takemoto Masaya, Shiraki Kimiyasu

Abstract excerpt

BACKGROUND: T-705 (favipiravir) is a potent inhibitor of RNA-dependent RNA polymerases of influenza viruses and no favipiravir-resistant virus has been isolated. Poliovirus RNA polymerase has been well characterized and isolation of resistant virus was examined in poliovirus. METHODS: Susceptibility variants of poliovirus I (Sabin strain) were isolated during passages in the presence of favipiravir and...

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PMID: 28709841
DOI: 10.1016/j.jmii.2017.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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