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Article

Polymorphisms in the DNA repair gene XRCC1 and age-related disease.

Mechanisms of ageing and development - 1 Jan 2003

Ladiges Warren, Wiley Jesse, MacAuley Alasdair

Abstract excerpt

The recent hypothesis that common variants (single nucleotide polymorphisms or SNPs) in the population may contribute significantly to genetic risk for common diseases permits a conceptually straightforward approach to identifying age-related disease-causing mutations. Functional variants of DNA replication and repair genes might be expected to be highly significant to cancer and aging since replication must...

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Source

Identifiers

PMID: 12618003
DOI: 10.1016/s0047-6374(02)00166-5

Genes

XRCC1
SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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