Article
Gene polymorphism and HLA-G expression in patients with childhood-onset systemic lupus erythematosus: A pilot study.
HLA - 1 Oct 2017
Cavalcanti A, Almeida R, Mesquita Z, Duarte A L B P, Donadi E A, Lucena-Silva N
Abstract excerpt
Human leukocyte antigen-G (HLA-G) presents inhibitory functions in immune cells and is located in a chromosomal region associated with systemic lupus erythematosus (SLE) susceptibility. Polymorphisms in 3' untranslated region (3'UTR) of HLA-G gene may influence protein expression. To date, no study analyzing HLA-G polymorphism and expression in childhood-onset systemic lupus erythematosus (cSLE) has been...
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