Article
JACUSA: site-specific identification of RNA editing events from replicate sequencing data.
BMC bioinformatics - 3 Jan 2017
Piechotta Michael, Wyler Emanuel, Ohler Uwe, Landthaler Markus, Dieterich Christoph
Abstract excerpt
BACKGROUND: RNA editing is a co-transcriptional modification that increases the molecular diversity, alters secondary structure and protein coding sequences by changing the sequence of transcripts. The most common RNA editing modification is the single base substitution (A→I) that is catalyzed by the members of the Adenosine deaminases that act on RNA (ADAR) family. Typically, editing sites are identified as...
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