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Article

CYP2B6 genotypes and early efavirenz-based HIV treatment outcomes in Botswana.

AIDS (London, England) - 24 Sept 2017

Gross Robert, Bellamy Scarlett L, Ratshaa Bakgaki, Han Xiaoyan, Vujkovic Marijana, Aplenc Richard, Steenhoff Andrew P, Mosepele Mosepele, Moorthy Ganesh, Zuppa Athena F, Strom Brian L, Bisson Gregory P

Abstract excerpt

OBJECTIVES: To determine the association between cytochrome p450 2B6 genotypes and efavirenz-based HIV treatment outcomes. DESIGN: Observational cohort study of HIV-infected adults initiating efavirenz-based regimens in Botswana. METHODS: The primary endpoint was a composite of death or loss to care or HIV RNA more than 25 copies/ml at 6 months. CYP2B6 516G>T and 983T>C genotyping was done with Taqman Open Array...

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Identifiers

PMID: 28692529
DOI: 10.1097/QAD.0000000000001593
PMCID: PMC5612381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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