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Article

Involvement of FANCD2 in Energy Metabolism via ATP5α.

Scientific reports - 7 Jul 2017

Jayabal Panneerselvam, Ma Chi, Nepal Manoj, Shen Yihang, Che Raymond, Turkson James, Fei Peiwen

Abstract excerpt

Growing evidence supports a general hypothesis that aging and cancer are diseases related to energy metabolism. However, the involvement of Fanconi Anemia (FA) signaling, a unique genetic model system for studying human aging or cancer, in energy metabolism remains elusive. Here, we report that FA complementation group D2 protein (FANCD2) functionally impacts mitochondrial ATP production through its interaction...

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Source

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Identifiers

PMID: 28687786
DOI: 10.1038/s41598-017-05150-1
PMCID: PMC5501830

Genes

FANCD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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