Article
Putative enhancer sites in the bovine genome are enriched with variants affecting complex traits.
Genetics, selection, evolution : GSE - 6 Jul 2017
Wang Min, Hancock Timothy P, MacLeod Iona M, Pryce Jennie E, Cocks Benjamin G, Hayes Benjamin J
Abstract excerpt
BACKGROUND: Enhancers are non-coding DNA sequences, which when they are bound by specific proteins increase the level of gene transcription. Enhancers activate unique gene expression patterns within cells of different types or under different conditions. Enhancers are key contributors to gene regulation, and causative variants that affect quantitative traits in humans and mice have been located in enhancer...
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