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Article

Regulation of retinal pigment epithelial cell phenotype by Annexin A8.

Scientific reports - 5 Jul 2017

Lueck Katharina, Carr Amanda-Jayne F, Stampoulis Dimitrios, Gerke Volker, Rescher Ursula, Greenwood John, Moss Stephen E

Abstract excerpt

The retinoic acid derivative fenretinide (FR) is capable of transdifferentiating cultured retinal pigment epithelial (RPE) cells towards a neuronal-like phenotype, but the underlying mechanisms are not understood. To identify genes involved in this process we performed a microarray analysis of RPE cells pre- and post-FR treatment, and observed a marked down-regulation of AnnexinA8 (AnxA8) in transdifferentiated...

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Identifiers

PMID: 28680125
DOI: 10.1038/s41598-017-03493-3
PMCID: PMC5498634

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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