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The footprint of the ageing stroma in older patients with breast cancer

3 Jul 2017

Abstract excerpt

BACKGROUND: Tumours are not only composed of malignant cells but also consist of a stromal micro-environment, which has been shown to influence cancer cell behaviour. Because the ageing process induces accumulation of senescent cells in the body, this micro-environment is thought to be different in cancers occurring in old patients compared with younger patients. More specifically, senescence-related fibroblastic...

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PMID: 28673354
DOI: 10.1186/s13058-017-0871-0

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