Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion.

Developmental biology - 1 Sept 2017

van Vliet Patrick P, Lin Lizhu, Boogerd Cornelis J, Martin James F, Andelfinger Gregor, Grossfeld Paul D, Evans Sylvia M

Abstract excerpt

Correct cardiac development is essential for fetal and adult life. Disruptions in a variety of signaling pathways result in congenital heart defects, including outflow and inflow tract defects. We previously found that WNT11 regulates outflow tract development. However, tissue specific requirements for WNT11 in this process remain unknown and whether WNT11 is required for inflow tract development has not been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Heart
Share to Hedgehog Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeobox Protein PITX2

Share to Integrases

Share to LIM-Homeodomain Proteins

Share to Mesoderm

Share to Organogenesis

Share to Wnt Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28669819
DOI: 10.1016/j.ydbio.2017.06.021
PMCID: PMC5580348

Genes

WNT11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion.PMID 28669819Read ↗

Wnt5a Is Required for Cardiac Outflow Tract Septation in MiceSemantic proximity Read ↗

Required, tissue-specific roles for Fgf8 in outflow tract formation and remodelingSemantic proximity Read ↗

Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development.Semantic proximity Read ↗

The Development of the Embryonic Outflow Tract Provides Novel Insights into Cardiac Differentiation and RemodelingSemantic proximity Read ↗

The mesodermal source of fibronectin is required for heart morphogenesis and cardiac outflow tract elongation by regulating cell shape, polarity, and mechanotransduction in the second heart fieldSemantic proximity Read ↗

Loss of Wnt5a disrupts second heart field cell deployment and may contribute to OFT malformations in DiGeorge syndromeSemantic proximity Read ↗

Sculpting the cardiac outflow tractSemantic proximity Read ↗

Vangl2-regulated polarisation of second heart field-derived cells is required for outflow tract lengthening during cardiac development.Semantic proximity Read ↗

BMP type II receptor regulates positioning of outflow tract and remodeling of atrioventricular cushion during cardiogenesisSemantic proximity Read ↗

Dysregulated endocardial TGFβ signaling and mesenchymal transformation result in heart outflow tract septation failure.Semantic proximity Read ↗

Wnt11 regulates cardiac chamber development and disease during perinatal maturationSemantic proximity Read ↗

The canonical Wingless signaling pathway is required but not sufficient for inflow tract formation in the Drosophila melanogaster heart.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.