Article
The canonical Wingless signaling pathway is required but not sufficient for inflow tract formation in the Drosophila melanogaster heart.
Developmental biology - 1 May 2016
Trujillo Gloriana V, Nodal Dalea H, Lovato Candice V, Hendren Jill D, Helander Lynda A, Lovato TyAnna L, Bodmer Rolf, Cripps Richard M
Abstract excerpt
The inflow tracts of the embryonic Drosophila cardiac tube, termed ostia, arise in its posterior three segments from cardiac cells that co-express the homeotic transcription factor Abdominal-A (abdA), the orphan nuclear receptor Seven-up (Svp), and the signaling molecule Wingless (Wg). To define the roles of these factors in inflow tract development, we assessed their function in inflow tract formation. We...
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