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Article

Spectrin and Other Membrane-Skeletal Components in Human Red Blood Cells of Different Age

1 Jan 2017

Abstract excerpt

BACKGROUND: Old human red blood cells (RBCs) have a reduced surface area with respect to young RBCs. If this decrease occurred through the release of vesicles similar to the spectrin-free vesicles that are shed in vitro under different experimental conditions or during storage, there would be no decrease of membrane-skeleton, but only of lipid bilayer surface area, during RBC ageing in vivo. However, we observed...

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PMID: 28668958
DOI: 10.1159/000478769

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