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Changes in the properties of normal human red blood cells during in vivo aging

27 Sept 2012

Abstract excerpt

The changes in red blood cells (RBC) as they age and the mechanisms for their eventual removal have been of interest for many years. Proposed age-related changes include dehydration with increased density and decreased size, increased membrane IgG, loss of membrane phospholipid asymmetry, and decreased activity of KCl cotransport. The biotin RBC label allows unambiguous identification of older cells and...

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PMID: 23115087
DOI: 10.1002/ajh.23344

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