Article
Aging and death signalling in mature red cells: from basic science to transfusion practice.
1 Jun 2010
Abstract excerpt
The red blood cells (RBCs) aging process is considered as an issue of special scientific and clinical interest. It represents a total of unidirectional, time-dependent but not-necessarily linear series of molecular events that finally lead to cell clearance1. Under normal circumstances, all human RBCs live approximately 120±4 days in blood circulation, implying the existence of tightly regulated molecular...
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