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Article

The effect of miR‐579 on the PI3K/AKT pathway in human glioblastoma PTEN mutant cell lines

26 Jun 2019

Abstract excerpt

Glioblastoma multiform (GBM) is a type of aggressive brain cancer with limited success in standard treatment. MicroRNAs are one of the most beneficial tools for diagnosis, prognosis, and treatment of cancer. This study aimed to investigate the effect of miR-579 on cellular behaviors and expression of PI3K/AKT signaling pathway in GBM cell lines. In the present study, miR-579 was overexpressed in U251 and A-172...

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PMID: 31243804
DOI: 10.1002/jcb.28935

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