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Article

Genetic association of FTO/IRX region with obesity and overweight in the Polish population.

PloS one - 1 Jan 2017

Sobalska-Kwapis Marta, Suchanecka Aleksandra, Słomka Marcin, Siewierska-Górska Anna, Kępka Ewa, Strapagiel Dominik

Abstract excerpt

BACKGROUND/OBJECTIVES: Genome-wide association studies (GWAS) have identified many loci associated with body mass index (BMI) in many different populations. Variants in the FTO locus are reported to be one of the strongest genetic predictors of obesity. Recent publications pointed also to a topologically associated domain (TAD) which is identified as a novel region affecting BMI. The TAD area encompasses the IRXB...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28662178
DOI: 10.1371/journal.pone.0180295
PMCID: PMC5491248

Genes

FTO
IRX3
IRX5
IRX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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