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Article

Deubiquitylation of deubiquitylases

1 Jun 2017

Abstract excerpt

Deubiquitylating enzymes (DUBs) reverse the ubiquitylation of target proteins, thereby regulating diverse cellular functions. In contrast to the plethora of research being conducted on the ability of DUBs to counter the degradation of cellular proteins or auto-ubiquitylated E3 ligases, very little is known about the mechanisms of DUB regulation. In this review paper, we summarize a novel possible mechanism of DUB...

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PMID: 28659380
DOI: 10.1098/rsob.170016

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