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Structural Effects of Single Mutations in a Filamentous Viral Capsid Across Multiple Length Scales.

Biomacromolecules - 14 Aug 2017

Abramov Gili, Shaharabani Rona, Morag Omry, Avinery Ram, Haimovich Anat, Oz Inbal, Beck Roy, Goldbourt Amir

Abstract excerpt

Filamentous bacteriophage (phage) are single-stranded DNA viruses that infect bacteria. Single-site mutants of fd phage have been studied by magic-angle spinning nuclear magnetic resonance and by small-angle X-ray scattering. Detailed analysis has been performed that provides insight into structural variations on three length scales. The results, analyzed in conjunction with existing literature data, suggest that...

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PMID: 28657731
DOI: 10.1021/acs.biomac.7b00125

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Source receipt: pubmed, retrieved 7 Sept 2026.

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