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Article

The early-onset preeclampsia is associated with MTHFR and FVL polymorphisms.

Archives of gynecology and obstetrics - 1 Jun 2015

Salimi Saeedeh, Saravani Mohsen, Yaghmaei Minoo, Fazlali Zeinab, Mokhtari Mojgan, Naghavi Anoosh, Farajian-Mashhadi Farzaneh

Abstract excerpt

PURPOSE: The aim of this study was to examine the association of factor V Leiden, prothrombin and methylenetetrahydrofolate reductase (MTHFR) polymorphisms and preeclampsia (PE) in Southeast of Iran. METHODS: This case-control study was performed on 192 preeclamptic and 196 normotensive pregnant women. Single nucleotide polymorphisms were genotyped using polymerase chain reaction-restriction fragment length...

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Identifiers

PMID: 25480409
DOI: 10.1007/s00404-014-3561-5

Genes

MTHFR

Variants

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