Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

Atherosclerosis - 1 Sept 2017

Berbée Jimmy F P, Mol Isabel M, Milne Ginger L, Pollock Erik, Hoeke Geerte, Lütjohann Dieter, Monaco Claudia, Rensen Patrick C N, van der Ploeg Lex H T, Shchepinov Mikhail S

Abstract excerpt

BACKGROUND AND AIMS: Oxidative modification of lipoproteins is a crucial step in atherosclerosis development. Isotopic-reinforced polyunsaturated fatty acids (D-PUFAs) are more resistant to reactive oxygen species-initiated chain reaction of lipid peroxidation than regular hydrogenated (H-)PUFAs. We aimed at investigating the effect of D-PUFA treatment on lipid peroxidation, hypercholesterolemia and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticholesteremic Agents
Share to Aortic Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E3

Share to Cholesterol Ester Transfer Proteins

Share to Dinoprost

Share to Fatty Acids, Unsaturated

Share to Lipid Peroxidation

Share to Mice, Knockout, ApoE

Source

Identifiers

PMID: 28655430
DOI: 10.1016/j.atherosclerosis.2017.06.916

Genes

APOE
CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.PMID 28655430Read ↗

Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice.Semantic proximity Read ↗

Zebrafish Models for Dyslipidemia and Atherosclerosis ResearchSemantic proximity Read ↗

Reducing Reactive Lipids Improves Cardiac Metabolic and Diastolic Function in Pulmonary Hypertension ModelsSemantic proximity Read ↗

Oxidized dietary lipids induce vascular inflammation and atherogenesis in post- menopausal rats: Estradiol and selected antihyperlipidemic drugs restore vascular health in vivoSemantic proximity Read ↗

Fatty Acids and Their Roles in Cardiac Physiology and Pathology: Mechanistic and Interventional StudiesSemantic proximity Read ↗

Scavenging dicarbonyls with 5’-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistanceSemantic proximity Read ↗

Transcriptomics as Precision Medicine to Classify <em>In Vivo</em> Models of Dietary-Induced Atherosclerosis at Cellular and Molecular LevelsSemantic proximity Read ↗

A high-fat diet with vitamin D and propylthiouracil produces a pro-atherogenic phenotype in rats.Semantic proximity Read ↗

4-oxo-2-nonenal Adducts In HDL Are Elevated In Familial Hypercholesterolemia: Identification Of Modified Sites And Functional ConsequencesSemantic proximity Read ↗

Dietary supplementation with long-chain monounsaturated fatty acid isomers decreases atherosclerosis and alters lipoprotein proteomes in LDLr-/- mice.Semantic proximity Read ↗

Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models.Semantic proximity Read ↗

Pseudocannabinoid H4CBD enhances lipid catabolism to reduce visceral adiposity and large adipocyte size in advanced metabolic syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.