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Article

Dietary supplementation with long-chain monounsaturated fatty acid isomers decreases atherosclerosis and alters lipoprotein proteomes in LDLr-/- mice.

Atherosclerosis - 1 Jul 2017

Yang Zhi-Hong, Gordon Scott M, Sviridov Denis, Wang Shuibang, Danner Robert L, Pryor Milton, Vaisman Boris, Shichijo Yuka, Doisaki Nobushige, Remaley Alan T

Abstract excerpt

BACKGROUND AND AIMS: Concentrated fish oils, containing a mixture of long-chain monounsaturated fatty acids (LCMUFA) with aliphatic chains longer than 18 C atoms (i.e., C20:1 and C22:1), have been shown to attenuate atherosclerosis development in mouse models. It is not clear, however, how individual LCMUFA isomers may act on atherosclerosis. METHODS: In the present study, we used saury fish oil-derived...

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Identifiers

PMID: 28486149
DOI: 10.1016/j.atherosclerosis.2017.04.017
PMCID: PMC7457543

Genes

CRP
LDLR

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