Article
Effect of VKORC1 and CYP2C9 polymorphisms on warfarin dose requirement in Bangladeshi population.
Pakistan journal of pharmaceutical sciences - 1 Mar 2017
Chowdhury Zahid Sadek, Shahjin Farah, Akter Farhana, Ahmed Maizbhauddin, Islam Mohammad Safiqul, Bin Sayeed Muhammad Shahdaat, Islam Reazul, Hasnat Abul
Abstract excerpt
Warfarin, an oral anticoagulant is one of the most widely prescribed drugs in modern medicine. Large inter-individuals variability due to age, gender, diet, concurrent drug interactions and variations in CYP2C9 and VKORC1 genes make the management of warfarin therapy challenging and yet no study has been conducted on the Bangladeshi population. The aim of the study was to identify the role of VKORC1 and CYP2C9...
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