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Article

Upregulated VEGF and Robo4 correlate with the reduction of miR-15a in the development of diabetic retinopathy

12 Apr 2019

Abstract excerpt

PURPOSE: Vascular endothelial growth factor (VEGF) plays implicated roles in diabetic retinopathy (DR). The role of roundabout 4 (Robo 4) in angiogenesis and vasculogenesis is controversial; however, the interdependent relationship between these two factors has not been studied in DR. This study determined the colocalization of VEGF and Robo4 in fibrovascular membranes (FVM) from patients with proliferative...

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PMID: 30980286
DOI: 10.1007/s12020-019-01921-0

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