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Article

PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway.

Journal of experimental & clinical cancer research : CR - 23 Jun 2017

Li Qiji, Ye Liping, Guo Wei, Wang Min, Huang Shuai, Peng Xinsheng

Abstract excerpt

BACKGROUND: PHF21B is newly identified to be involved in the tumor progression; however, its biological role and molecular mechanism in prostate cancer have not been defined. This study is aimed to study the role of PHF21B in the progression of prostate cancer. METHODS: Real-time PCR, immunohistochemistry and western blotting analysis were used to determine PHF21B expression in prostate cancer cell lines and...

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Identifiers

PMID: 28645312
DOI: 10.1186/s13046-017-0560-y
PMCID: PMC5481925

Genes

SFRP1
SFRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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