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Article

Molecular dynamics study of membrane permeabilization by wild-type and mutant lytic peptides from the non-enveloped Flock House virus.

Biochimica et biophysica acta. Biomembranes - 1 Feb 2020

Nangia Shivangi, Boyd Kevin J, May Eric R

Abstract excerpt

Flock House virus (FHV) serves as a model system for understanding infection mechanisms utilized by non-enveloped viruses to transport across cellular membranes. During the infection cycle of FHV, a fundamental stage involves disruption of the endosomal membrane by membrane active peptides, following externalization of the peptides from the capsid interior. The FHV lytic agents are the 44 C-terminal amino acids...

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Identifiers

PMID: 31678020
DOI: 10.1016/j.bbamem.2019.183102
PMCID: PMC6943179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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