Article
TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa.
Proceedings of the National Academy of Sciences of the United States of America - 3 Jul 2017
Castaneda Julio M, Hua Rong, Miyata Haruhiko, Oji Asami, Guo Yueshuai, Cheng Yiwei, Zhou Tao, Guo Xuejiang, Cui Yiqiang, Shen Bin, Wang Zibin, Hu Zhibin, Zhou Zuomin, Sha Jiahao, Prunskaite-Hyyrylainen Renata, Yu Zhifeng, Ramirez-Solis Ramiro, Ikawa Masahito, Matzuk Martin M, Liu Mingxi
Abstract excerpt
Flagella and cilia are critical cellular organelles that provide a means for cells to sense and progress through their environment. The central component of flagella and cilia is the axoneme, which comprises the "9+2" microtubule arrangement, dynein arms, radial spokes, and the nexin-dynein regulatory complex (N-DRC). Failure to properly assemble components of the axoneme leads to defective flagella and in humans...
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