Article
Alternative splicing and start sites: Lessons from the Grainyhead-like family.
Developmental biology - 1 Sept 2017
Miles Lee B, Dworkin Sebastian, Darido Charbel
Abstract excerpt
The two main mechanisms that expand the proteomic output of eukaryotic genes are alternative splicing and alternative translation initiation signals. Despite being essential to generate isoforms of gene products that create functional diversity during development, the impact of these mechanisms on fine-tuning regulatory gene networks is still underappreciated. In this review, we use the Grainyhead-like (Grhl)...
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