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Neural Tube Defects, Folic Acid and Methylation

17 Sept 2013

Abstract excerpt

Neural tube defects (NTDs) are common complex congenital malformations resulting from failure of the neural tube closure during embryogenesis. It is established that folic acid supplementation decreases the prevalence of NTDs, which has led to national public health policies regarding folic acid. To date, animal studies have not provided sufficient information to establish the metabolic and/or genomic...

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PMID: 24048206
DOI: 10.3390/ijerph10094352

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