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Article

Oxidized LDL activated eosinophil polarize macrophage phenotype from M2 to M1 through activation of CD36 scavenger receptor.

Atherosclerosis - 1 Aug 2017

Qin Minghui, Wang Lai, Li Fuqiang, Yang Mingjie, Song Lei, Tian Fang, Yukht Ada, Shah Prediman K, Rothenberg Marc E, Sharifi Behrooz G

Abstract excerpt

BACKGROUND AND AIMS: Inflammation, particularly innate immunity, plays an important role in cardiovascular diseases. The aim of this study was to investigate whether atherogenic determinants such as oxidized LDL modulate the phenotype of eosinophils. METHODS: Cultured eosinophils were treated with oxidized LDL and the expression of selective inflammatory and anti-inflammatory cytokines was determined. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD36 Antigens

Share to Culture Media, Conditioned

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Share to Lipoproteins, LDL

Share to Macrophages, Peritoneal

Share to Scavenger Receptors, Class B

Source

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Identifiers

PMID: 28623741
DOI: 10.1016/j.atherosclerosis.2017.05.011
PMCID: PMC5557672

Genes

ARG1
CCL24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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