Article
Characterization and Targeting of Platelet-Derived Growth Factor Receptor alpha (PDGFRA) in Inflammatory Breast Cancer (IBC).
Neoplasia (New York, N.Y.) - 1 Jul 2017
Joglekar-Javadekar Madhura, Van Laere Steven, Bourne Michael, Moalwi Manal, Finetti Pascal, Vermeulen Peter B, Birnbaum Daniel, Dirix Luc Y, Ueno Naoto, Carter Monique, Rains Justin, Ramachandran Abhijit, Bertucci Francois, van Golen Kenneth L
Abstract excerpt
PURPOSE: Inflammatory breast cancer (IBC) is arguably the deadliest form of breast cancer due to its rapid onset and highly invasive nature. IBC carries 5- and 10-year disease-free survival rates of ~45% and <20%, respectively. Multiple studies demonstrate that in comparison with conventional breast cancer, IBC has a unique molecular identity. Here, we have identified platelet-derived growth factor receptor alpha...
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