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Article

A Fast and Accurate Algorithm to Test for Binary Phenotypes and Its Application to PheWAS.

American journal of human genetics - 6 Jul 2017

Dey Rounak, Schmidt Ellen M, Abecasis Goncalo R, Lee Seunggeun

Abstract excerpt

The availability of electronic health record (EHR)-based phenotypes allows for genome-wide association analyses in thousands of traits and has great potential to enable identification of genetic variants associated with clinical phenotypes. We can interpret the phenome-wide association study (PheWAS) result for a single genetic variant by observing its association across a landscape of phenotypes. Because a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28602423
DOI: 10.1016/j.ajhg.2017.05.014
PMCID: PMC5501775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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