Article

A fast and accurate algorithm to test for binary phenotypes and its application to PheWAS

2017-02-20

Abstract excerpt

The availability of electronic health record (EHR)-based phenotypes allows for genome-wide association analyses in thousands of traits, and has great potential to identify novel genetic variants associated with clinical phenotypes. We can interpret the phenome-wide association study (PheWAS) result for a single genetic variant by observing its association across a landscape of phenotypes. Since PheWAS can test 100...

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Literature Corpus work: 42d6cb32-28dc-51d5-8890-81b2f006e938
DOI: 10.1101/109876

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