Article
Apolipoprotein E polymorphism and the risk of aneurysmal subarachnoid hemorrhage in a South Indian population.
Cellular & molecular biology letters - 1 Jan 2017
Suvatha Arati, Kandi Sibin Madathan, Bhat Dhananjaya Ishwara, Rao Narasinga, Vazhayil Vikas, Kasturirangan Chetan Ghati
Abstract excerpt
BACKGROUND: The rupture of a brain aneurysm causes bleeding in the subarachnoid space. This is known as aneurysmal subarachnoid hemorrhage (aSAH). We evaluated the association of apolipoprotein E (APOE) polymorphism and the risk of aSAH in a South Indian population. METHODS: The study was performed on 200 subjects with aSAH and 253 healthy control subjects. Blood samples (5 ml) were used to isolate DNA and...
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