Article
Investigating Cryopreserved PBMC Functionality in an Antigen-Induced Model of Sarcoidosis Granuloma Formation
2024-03-27
Abstract excerpt
Sarcoidosis, a systemic inflammatory disease, poses challenges in understanding its etiology and variable clinical courses. Despite ongoing uncertainty about causative agents and genetic predisposition, granuloma formation remains its hallmark feature. To address this complexity, we developed a validated in vitro human granuloma model using peripheral blood mononuclear cells (PBMCs), providing a dynamic platform f...
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Identifiers and source
- Literature Corpus work
- c67e2a42-4512-51c5-aa6a-561031253ab2
- DOI
- 10.1101/2024.03.23.586344