Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Splice variants as novel targets in pancreatic ductal adenocarcinoma

1 Jun 2017

Abstract excerpt

Despite a wealth of genomic information, a comprehensive alternative splicing (AS) analysis of pancreatic ductal adenocarcinoma (PDAC) has not been performed yet. In the present study, we assessed whole exome-based transcriptome and AS profiles of 43 pancreas tissues using Affymetrix exon array. The AS analysis of PDAC indicated on average two AS probe-sets (ranging from 1-28) in 1,354 significantly identified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pancreatic and Hepatic Oncology Research
Share to RNA modifications and cancer
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28592875
DOI: 10.1038/s41598-017-03354-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Splice variants as novel targets in pancreatic ductal adenocarcinomaPMID 28592875Read ↗

Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk.Semantic proximity Read ↗

Prediction of pancreatic adenocarcinoma patient risk status using alternative splicing eventsSemantic proximity Read ↗

Prediction of pancreatic adenocarcinoma patient risk status using alternative splicing eventsSemantic proximity Read ↗

An alternative splicing signature defines the basal-like phenotype and predicts worse clinical outcome in pancreatic cancer.Semantic proximity Read ↗

Drivers of Gene Expression Dysregulation in Pancreatic Cancer.Semantic proximity Read ↗

A central research portal for mining pancreatic clinical and molecular datasets and accessing biobanked samplesSemantic proximity Read ↗

Alternative polyadenylation characterizes epithelial and fibroblast phenotypic heterogeneity in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Alternative polyadenylation drives oncogenic gene expression in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

An integrative RNA spliceosomic landscape of pancreatic neuroendocrine tumors unveils novel clinicomolecular associationsSemantic proximity Read ↗

Whole exome sequencing and RNA sequencing analyses of PDAC samplesSemantic proximity Read ↗

An Exosome-based Transcriptomic Signature for Noninvasive, Early Detection of Patients With Pancreatic Ductal Adenocarcinoma: A Multicenter Cohort StudySemantic proximity Read ↗

Specificity of Aberrant Exons in a Saturated Background of Differentially Expressed ExonsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.