Article
Prevalence of pre-treatment hepatitis C virus NS5A resistance associated amino-acid substitutions in genotype 1A infected patients in Scotland.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2018
Bradley-Stewart Amanda, Goldstein Emily, MacLean Alasdair, Gunson Rory
Abstract excerpt
BACKGROUND: Hepatitis C (HCV) NS5A resistance associated amino-acid substitutions (RAS) can exist at baseline in treatment naïve individuals and have been shown to be associated with lower rates of sustained virological response (SVR) for patients infected with HCV genotype 1A (G1A) following treatment with NS5A inhibitors. OBJECTIVES: The aim of this study was to measure the prevalence of baseline NS5A...
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